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Inducible expression of Wnt7b promotes bone formation in aged mice and enhances fracture healing

There remain unmet clinical needs for safe and effective bone anabolic therapies to treat aging-related osteoporosis and to improve fracture healing in cases of nonunion or delayed union. Wnt signaling has emerged as a promising target pathway for developing novel bone anabolic drugs. Although neutr...

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Détails bibliographiques
Publié dans:Bone Res
Auteurs principaux: Song, Deye, He, Guangxu, Song, Fangfang, Wang, Zhepeng, Liu, Xiaochen, Liao, Lele, Ni, Jiangdong, Silva, Matthew J., Long, Fanxin
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997361/
https://ncbi.nlm.nih.gov/pubmed/32047703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-019-0081-8
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