Tumor microenvironment and breast cancer survival: combined effects of breast fat, M2 macrophages and hyaluronan create a dismal prognosis

PURPOSE: Tumor microenvironment, including inflammatory cells, adipocytes and extracellular matrix constituents such as hyaluronan (HA), impacts on cancer progression. Systemic metabolism also influences tumor growth e.g. obesity and type 2 diabetes (T2D) are risk factors for breast cancer. Here, in...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Tiainen, Satu, Masarwah, Amro, Oikari, Sanna, Rilla, Kirsi, Hämäläinen, Kirsi, Sudah, Mazen, Sutela, Anna, Vanninen, Ritva, Ikonen, Juho, Tammi, Raija, Tammi, Markku, Auvinen, Päivi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
Assuntos:
Preclinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997252/
https://ncbi.nlm.nih.gov/pubmed/31720917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-019-05491-7
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