Modulation of Keap1/Nrf2/ARE Signaling Pathway by Curcuma- and Garlic-Derived Hybrids

Nrf2 is a basic leucine zipper transcription factor that binds to the promoter region of the antioxidant response element (ARE), inducing the coordinated up-regulation of antioxidant and detoxification genes. We recently synthesized a set of new molecules by combining the functional moieties of curc...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Autores principales: Serafini, Melania Maria, Catanzaro, Michele, Fagiani, Francesca, Simoni, Elena, Caporaso, Roberta, Dacrema, Marco, Romanoni, Irene, Govoni, Stefano, Racchi, Marco, Daglia, Maria, Rosini, Michela, Lanni, Cristina
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997134/
https://ncbi.nlm.nih.gov/pubmed/32047434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01597
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