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Effect of PAK Inhibition on Cell Mechanics Depends on Rac1

Besides biochemical and molecular regulation, the migration and invasion of cells is controlled by the environmental mechanics and cellular mechanics. Hence, the mechanical phenotype of cells, such as fibroblasts, seems to be crucial for the migratory capacity in confined 3D extracellular matrices....

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Bibliografiske detaljer
Udgivet i:Front Cell Dev Biol
Main Authors: Mierke, Claudia Tanja, Puder, Stefanie, Aermes, Christian, Fischer, Tony, Kunschmann, Tom
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997127/
https://ncbi.nlm.nih.gov/pubmed/32047750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00013
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