Jupiter microtubule‐associated homolog 1 (JPT1): A predictive and pharmacodynamic biomarker of metformin response in endometrial cancers

Preoperative use of metformin in obese women with endometrioid endometrial cancer (EEC) reduces tumor proliferation and inhibits the mammalian target of rapamycin pathway, though is only effective in select cases. This study sought to identify a predictive and/or pharmacodynamic proteomic signature...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Bateman, Nicholas W., Teng, Pang‐Ning, Hope, Erica, Hood, Brian L., Oliver, Julie, Ao, Wei, Zhou, Ming, Wang, Guisong, Tommarello, Domenic, Wilson, Katlin, Litzy, Tracy, Conrads, Kelly A., Hamilton, Chad A., Darcy, Kathleen M., Casablanca, Yovanni, Maxwell, George Larry, Bae‐Jump, Victoria, Conrads, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997075/
https://ncbi.nlm.nih.gov/pubmed/31808620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2729
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