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Human UDP-galactose 4′-epimerase (GALE) is required for cell-surface glycome structure and function
Glycan biosynthesis relies on nucleotide sugars (NSs), abundant metabolites that serve as monosaccharide donors for glycosyltransferases. In vivo, signal-dependent fluctuations in NS levels are required to maintain normal cell physiology and are dysregulated in disease. However, how mammalian cells...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6996900/ https://ncbi.nlm.nih.gov/pubmed/31819007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009271 |
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