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Proteasome inhibition creates a chromatin landscape favorable to RNA Pol II processivity

Proteasome activity is required for diverse cellular processes, including transcriptional and epigenetic regulation. However, inhibiting proteasome activity can lead to an increase in transcriptional output that is correlated with enriched levels of trimethyl H3K4 and phosphorylated forms of RNA pol...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Kinyamu, H. Karimi, Bennett, Brian D., Bushel, Pierre R., Archer, Trevor K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996893/
https://ncbi.nlm.nih.gov/pubmed/31806706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011174
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