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Respiratory supercomplexes act as a platform for complex III‐mediated maturation of human mitochondrial complexes I and IV
Mitochondrial respiratory chain (MRC) enzymes associate in supercomplexes (SCs) that are structurally interdependent. This may explain why defects in a single component often produce combined enzyme deficiencies in patients. A case in point is the alleged destabilization of complex I in the absence...
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| Publicado no: | EMBO J |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6996572/ https://ncbi.nlm.nih.gov/pubmed/31912925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102817 |
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