Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation

To understand the molecular mechanisms that mediate the anti-hepatitis B virus (HBV) effect of interferon (IFN) therapy, we conduct high-throughput bimolecular fluorescence complementation screening to identify potential physical interactions between the HBx protein and 145 IFN-stimulated genes (ISG...

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Vydáno v:Cell Rep
Hlavní autoři: Tan, Guangyun, Yi, Zhaohong, Song, Hongxiao, Xu, Fengchao, Li, Feng, Aliyari, Roghiyh, Zhang, Hong, Du, Peishuang, Ding, Yanhua, Niu, Junqi, Wang, Xiaosong, Su, Lishan, Qin, F. Xiao-Feng, Cheng, Genhong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996557/
https://ncbi.nlm.nih.gov/pubmed/31825835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.11.041
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