Dramatic increase in gene mutational burden after transformation of follicular lymphoma into TdT(+) B-lymphoblastic leukemia/lymphoma

Transformation of follicular lymphoma (FL) into B-lymphoblastic leukemia/lymphoma (B-ALL/LBL) is rare and results in greatly increased aggressiveness of clinical course. Here we present extensive molecular analysis of this unusual transformation, including immunoglobulin (Ig) gene rearrangement stud...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Mol Case Stud
Main Authors: Belman, Jonathan P., Meng, Wenzhao, Wang, Hong Yi, Li, Jie, Strauser, Honore T., Rosenfeld, Aaron M., Zhang, Qian, Prak, Eline T. Luning, Wasik, Mariusz
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996523/
https://ncbi.nlm.nih.gov/pubmed/31776129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a004614
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