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Icosabutate Exerts Beneficial Effects Upon Insulin Sensitivity, Hepatic Inflammation, Lipotoxicity, and Fibrosis in Mice

Icosabutate is a structurally engineered eicosapentaenoic acid derivative under development for nonalcoholic steatohepatitis (NASH). In this study, we investigated the absorption and distribution properties of icosabutate in relation to liver targeting and used rodents to evaluate the effects of ico...

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書目詳細資料
發表在:Hepatol Commun
Main Authors: van den Hoek, Anita M., Pieterman, Elsbet J., van der Hoorn, José W., Iruarrizaga‐Lejarreta, Marta, Alonso, Cristina, Verschuren, Lars, Skjæret, Tore, Princen, Hans M.G., Fraser, David A.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996349/
https://ncbi.nlm.nih.gov/pubmed/32025605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1453
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