Genotypic and phenotypic characterization of West Nile virus NS5 methyltransferase mutants

Although West Nile virus (WNV) causes annual cases of neurological disease and deaths in humans, a vaccine has not been licensed for human use. Several WNV genes have been targeted for mutagenesis in attempts to generate live attenuated vaccine candidates, including the non-structural protein NS5. S...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Kaiser, Jaclyn A., Luo, Huanle, Widen, Steven G., Wood, Thomas G., Huang, Claire Y.-H., Wang, Tian, Barrett, Alan D.T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996054/
https://ncbi.nlm.nih.gov/pubmed/31611100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2019.09.045
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