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A Novel COL4A5 Splicing Mutation Causes Skipping of Exon 14 in a Chinese Family with Alport Syndrome

BACKGROUND: Alport syndrome (AS) is an inherited progressive renal disease caused by mutations in COL4A3, COL4A4, and COL4A5. Although mutation screening in the genes responsible for AS is typically performed, only a small proportion of patients receive genetic testing in China, and the functional c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Kidney Dis (Basel)
Hauptverfasser: Gao, Erzhi, Yang, Xi, Si, Nuo, Liu, Keqiang, Wang, Jin-Quan, Liu, Zhihong
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995980/
https://ncbi.nlm.nih.gov/pubmed/32021873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000502798
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