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Lanatoside C Induces G2/M Cell Cycle Arrest and Suppresses Cancer Cell Growth by Attenuating MAPK, Wnt, JAK-STAT, and PI3K/AKT/mTOR Signaling Pathways
Cardiac glycosides (CGs) are a diverse family of naturally derived compounds having a steroid and glycone moiety in their structures. CG molecules inhibit the α-subunit of ubiquitous transmembrane protein Na(+)/K(+)-ATPase and are clinically approved for the treatment of cardiovascular diseases. Rec...
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| Veröffentlicht in: | Biomolecules |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6995510/ https://ncbi.nlm.nih.gov/pubmed/31783627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9120792 |
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