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Lanatoside C Induces G2/M Cell Cycle Arrest and Suppresses Cancer Cell Growth by Attenuating MAPK, Wnt, JAK-STAT, and PI3K/AKT/mTOR Signaling Pathways

Cardiac glycosides (CGs) are a diverse family of naturally derived compounds having a steroid and glycone moiety in their structures. CG molecules inhibit the α-subunit of ubiquitous transmembrane protein Na(+)/K(+)-ATPase and are clinically approved for the treatment of cardiovascular diseases. Rec...

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Dades bibliogràfiques
Publicat a:Biomolecules
Autors principals: Reddy, Dhanasekhar, Kumavath, Ranjith, Ghosh, Preetam, Barh, Debmalya
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995510/
https://ncbi.nlm.nih.gov/pubmed/31783627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9120792
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