Generation and characterization of Lhx4(tdT) reporter knock-in and Lhx4(loxP) conditional knockout mice

LHX4 is a LIM-homeodomain transcription factor essential for the development of spinal cord and pituitary gland. Mice with homozygous Lhx4-null mutation suffer early postnatal death from lung defect. In this study, to facilitate the research on Lhx4 function, we designed a targeting construct to gen...

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Bibliographic Details
Published in:Genesis
Main Authors: Dong, Xuhui, Xie, Xiaoling, Guo, Luming, Xu, Jiadong, Xu, Mei, Liang, Guoqing, Gan, Lin
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995401/
https://ncbi.nlm.nih.gov/pubmed/31313880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.23328
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