Functional characterization of full-length BARD1 strengthens its role as a tumor suppressor in neuroblastoma

BARD1 is associated with the development of high-risk neuroblastoma patients. Particularly, the expression of full length (FL) isoform, FL BARD1, correlates to high-risk neuroblastoma development and its inhibition is sufficient to induce neuroblastoma cells towards a worst phenotype. Here we have i...

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Veröffentlicht in:J Cancer
Hauptverfasser: Cimmino, Flora, Avitabile, Marianna, Lasorsa, Vito Alessandro, Pezone, Lucia, Cardinale, Antonella, Montella, Annalaura, Cantalupo, Sueva, Iolascon, Achille, Capasso, Mario
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995383/
https://ncbi.nlm.nih.gov/pubmed/32047556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.36164
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