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A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications

There is a growing awareness that complex 3-dimensional (3D) organs are not well represented by monolayers of a single cell type – the standard format for many drug screens. To address this deficiency, and with the goal of improving screens so that drugs with good efficacy and low toxicity can be id...

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Détails bibliographiques
Publié dans:Lab Chip
Auteurs principaux: Phan, Duc T.T., Wang, Xiaolin, Craver, Brianna M., Sobrino, Agua, Zhao, Da, Chen, Jerry C., Lee, Lilian Y.N., George, Steven C., Lee, Abraham P., Hughes, Christopher C.W.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995340/
https://ncbi.nlm.nih.gov/pubmed/28092382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6lc01422d
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