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Multi-dimensional omics characterization in glioblastoma identifies the purity-associated pattern and prognostic gene signatures

BACKGROUND: The presence of tumor-associated stroma and tumor-infiltrated immune cells have been largely reported across glioblastomas. Tumor purity, defined as the proportion of tumor cells in the tumor, was associated with the genomic and clinicopathologic features of the tumor and may alter the i...

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Bibliographic Details
Published in:Cancer Cell Int
Main Authors: Xiong, Yi, Xiong, Zujian, Cao, Hang, Li, Chang, Wanggou, Siyi, Li, Xuejun
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995093/
https://ncbi.nlm.nih.gov/pubmed/32021566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-1116-3
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