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The Anchored Flexibility Model in LC8 Motif Recognition: Insights from the Chica Complex

LC8 is a dimeric hub protein involved in a large number of interactions central to cell function. It binds short linear motifs—usually containing a Thr-Gln-Thr (TQT) triplet—in intrinsically disordered regions of its binding partners, some of which have several LC8 recognition motifs in tandem. Hall...

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Détails bibliographiques
Publié dans:Biochemistry
Auteurs principaux: Clark, Sarah, Nyarko, Afua, Löhr, Frank, Karplus, P. Andrew, Barbar, Elisar
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995037/
https://ncbi.nlm.nih.gov/pubmed/26652654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01099
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