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BAG6 contributes to glucose uptake by supporting the cell surface translocation of the glucose transporter GLUT4

Defective translocation of glucose transporter 4 (GLUT4) to the cell surface is a key feature of insulin resistance in type 2 diabetes. Therefore, elucidating the mechanism of GLUT4 translocation is of primary importance. The mammalian Bag6/Bat3 gene has been suggested to be linked with potential ob...

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Dettagli Bibliografici
Pubblicato in:Biol Open
Autori principali: Minami, Setsuya, Yokota, Naoto, Kawahara, Hiroyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994957/
https://ncbi.nlm.nih.gov/pubmed/31911483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.047324
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