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miR-155 Overexpression in OT-1 CD8(+) T Cells Improves Anti-Tumor Activity against Low-Affinity Tumor Antigen
Therapy by adoptive transfer of ex vivo-expanded tumor-infiltrating or genetically modified T cells may lead to impressive clinical responses. However, there is a need to improve in vivo persistence and functionality of the transferred T cells, in particular, to face the highly immunosuppressive env...
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| Publicado no: | Mol Ther Oncolytics |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Gene & Cell Therapy
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6994712/ https://ncbi.nlm.nih.gov/pubmed/32021906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2019.12.008 |
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