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Sensitive Automated Measurement of Histone-DNA Affinities in Nucleosomes

The DNA of eukaryotes is wrapped around histone octamers to form nucleosomes. Although it is well established that the DNA sequence significantly influences nucleosome formation, its precise contribution has remained controversial, partially owing to the lack of quantitative affinity data. Here, we...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Schnepf, Max, Ludwig, Claudia, Bandilla, Peter, Ceolin, Stefano, Unnerstall, Ulrich, Jung, Christophe, Gaul, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994541/
https://ncbi.nlm.nih.gov/pubmed/31982782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100824
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