Vaccination with virosomally formulated recombinant CyRPA elicits protective antibodies against Plasmodium falciparum parasites in preclinical in vitro and in vivo models

The Plasmodium falciparum (Pf) cysteine-rich protective antigen (PfCyRPA) has emerged as a promising blood-stage candidate antigen for inclusion into a broadly cross-reactive malaria vaccine. This highly conserved protein among various geographical strains plays a key role in the red blood cell inva...

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Vydáno v:NPJ Vaccines
Hlavní autoři: Tamborrini, Marco, Hauser, Julia, Schäfer, Anja, Amacker, Mario, Favuzza, Paola, Kyungtak, Kwak, Fleury, Sylvain, Pluschke, Gerd
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994490/
https://ncbi.nlm.nih.gov/pubmed/32025340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-0158-9
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