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Differential functional patterns of memory CD4(+) and CD8(+) T-cells from volunteers immunized with Ty21a typhoid vaccine observed using a recombinant Escherichia coli system expressing S. Typhi proteins

It is widely accepted that CD4(+) and CD8(+) T-cells play a significant role in protection against Salmonella enterica serovar Typhi (S. Typhi), the causative agent of the typhoid fever. However, the antigen specificity of these T-cells remains largely unknown. Previously, we demonstrated the feasib...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Salerno-Gonçalves, Rosângela, Tettelin, Hervé, Luo, David, Guo, Qin, Ardito, Matthew T., Martin, William D., De Groot, Anne S., Sztein, Marcelo B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994170/
https://ncbi.nlm.nih.gov/pubmed/31629569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2019.10.020
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