Antigen-loaded monocyte administration induces potent therapeutic antitumor T cell responses

Efficacy of dendritic cell (DC) cancer vaccines is classically thought to depend on their antigen-presenting cell (APC) activity. Studies show, however, that DC vaccine priming of cytotoxic T lymphocytes (CTLs) requires the activity of endogenous DCs, suggesting that exogenous DCs stimulate antitumo...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Huang, Min-Nung, Nicholson, Lowell T., Batich, Kristen A., Swartz, Adam M., Kopin, David, Wellford, Sebastian, Prabhakar, Vijay K., Woroniecka, Karolina, Nair, Smita K., Fecci, Peter E., Sampson, John H., Gunn, Michael D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2020
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994156/
https://ncbi.nlm.nih.gov/pubmed/31661470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI128267
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