Glucocorticoids paradoxically facilitate steroid resistance in T cell acute lymphoblastic leukemias and thymocytes

Glucocorticoids (GCs) are a central component of therapy for patients with T cell acute lymphoblastic leukemia (T-ALL), and although resistance to GCs is a strong negative prognostic indicator in T-ALL, the mechanisms of GC resistance remain poorly understood. Using diagnostic samples from patients...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Meyer, Lauren K., Huang, Benjamin J., Delgado-Martin, Cristina, Roy, Ritu P., Hechmer, Aaron, Wandler, Anica M., Vincent, Tiffaney L., Fortina, Paolo, Olshen, Adam B., Wood, Brent L., Horton, Terzah M., Shannon, Kevin M., Teachey, David T., Hermiston, Michelle L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994137/
https://ncbi.nlm.nih.gov/pubmed/31687977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130189
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki