Genetic polymorphism in C3 is associated with progression in chronic kidney disease (CKD) patients with IgA nephropathy but not in other causes of CKD

OBJECTIVES: The R102G variant in complement 3 (C3) results in two allotypic variants: C3 fast (C3F) and C3 slow (C3S). C3F presents at increased frequency in patients with chronic kidney disease (CKD), our aim is to explore its role in CKD progression and mortality. METHODS: Delta (Δ) eGFR for 2038...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Ibrahim, Sara T., Chinnadurai, Rajkumar, Ali, Ibrahim, Payne, Debbie, Rice, Gillian I., Newman, William G., Algohary, Eman, Adam, Ahmed G., Kalra, Philip A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994105/
https://ncbi.nlm.nih.gov/pubmed/32004338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228101
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