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Clonal rolling circle amplification for on-chip DNA cluster generation
Generation of monoclonal DNA clusters on a surface is a useful method for digital nucleic acid detection applications (e.g. microarray or next-generation sequencing). To obtain sufficient copies per cluster for digital detection, the single molecule bound to the surface must be amplified. Here we de...
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| 發表在: | Biol Methods Protoc |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6994026/ https://ncbi.nlm.nih.gov/pubmed/32161790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biomethods/bpx007 |
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