Immune responses to Mycobacterium tuberculosis membrane-associated antigens including alpha crystallin can potentially discriminate between latent infection and active tuberculosis disease

Changes in expression of membrane antigens may accompany the transition of Mycobacterium tuberculosis (Mtb) from ‘dormant’ to ‘active’ states. We have determined whether antibody and T cell responses to Mtb membrane (MtM)-associated antigens, especially the latency-induced protein alpha crystallin (...

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Bibliographic Details
Published in:PLoS One
Main Authors: Kumar, Shashi Kant, Arya, Suvrat, Aggarwal, Amita, Kapoor, Prerna, Nath, Alok, Misra, Ramnath, Sinha, Sudhir
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994005/
https://ncbi.nlm.nih.gov/pubmed/32004357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228359
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