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Bleomycin Induces Drug Efflux in Lungs. A Pitfall for Pharmacological Studies of Pulmonary Fibrosis

ATP-binding cassette (ABC) transporters are evolutionarily conserved membrane proteins that pump a variety of endogenous substrates across cell membranes. Certain subfamilies are known to interact with pharmaceutical compounds, potentially influencing drug delivery and treatment efficacy. However, t...

詳細記述

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書誌詳細
出版年:Am J Respir Cell Mol Biol
主要な著者: Park, Joshua K., Coffey, Nathan J., Bodine, Steven P., Zawatsky, Charles N., Jay, Lindsey, Gahl, William A., Kunos, George, Gochuico, Bernadette R., Malicdan, May Christine V., Cinar, Resat
フォーマット: Artigo
言語:Inglês
出版事項: American Thoracic Society 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993545/
https://ncbi.nlm.nih.gov/pubmed/31419911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0147OC
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