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Substance P participates in periodontitis by upregulating HIF-1α and RANKL/OPG ratio

BACKGROUND: Both substance P and hypoxia-inducible factor 1 alpha (HIF-1α) are involved in inflammation and angiogenesis. However, the relationship between substance P and HIF-1α in rat periodontitis is still unknown. METHODS: Ligation-induced rat periodontitis was established to observe the distrib...

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Dettagli Bibliografici
Pubblicato in:BMC Oral Health
Autori principali: Yan, Kaixian, Lin, Qin, Tang, Kailiang, Liu, Shuang, Du, Yi, Yu, Xijiao, Li, Shu
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993464/
https://ncbi.nlm.nih.gov/pubmed/32000757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12903-020-1017-9
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