Does Xpert® MTB/RIF assay give rifampicin resistance results without identified mutation? Review of cases from Addis Ababa, Ethiopia

BACKGROUND: Xpert® MTB/RIF assay is currently used in Ethiopia for the rapid diagnosis of Mycobacterium tuberculosis (MTB) and mutations that confer Rifampicin resistance. Rifampicin resistance is determined based on any mutation in the 81 bp of rpoB gene using five overlapping probes represented as...

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Pubblicato in:BMC Infect Dis
Autori principali: Alemu, Ayinalem, Tadesse, Mengistu, Seid, Getachew, Mollalign, Helina, Eshetu, Kirubel, Sinshaw, Waganeh, Abebaw, Yeshiwork, Amare, Misikir, Dagne, Biniyam, Diriba, Getu, Yenew, Bazezew, Getu, Melak, Zerihun, Betselot
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993378/
https://ncbi.nlm.nih.gov/pubmed/32000702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-020-4817-2
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