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ALKBH5-mediated m(6)A demethylation of lncRNA PVT1 plays an oncogenic role in osteosarcoma
BACKGROUND: Osteosarcoma (OS) is one of the most common malignant bone tumors. Plasmacytoma variant translocation 1 (PVT1) is a well-known oncogenic long noncoding RNA (lncRNA). However, to date, the regulatory mechanism of PVT1 upregulation in OS remains unknown. METHODS: qRT-PCR was carried out to...
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| Vydáno v: | Cancer Cell Int |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6993345/ https://ncbi.nlm.nih.gov/pubmed/32021563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-1105-6 |
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