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Monitoring DNA Breaks in Optically Highlighted Chromatin in Living Cells by Laser Scanning Confocal Microscopy

The recognition and repair of DNA lesions occurs within a chromatin environment. Genetically tagging fluorescent proteins to DNA damage response proteins has provided spatial and temporal details concerning the establishment of biochemical subnuclear regions geared toward metabolizing genomic lesion...

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Detalles Bibliográficos
Publicado en:Methods Mol Biol
Main Authors: Kruhlak, Michael J., Celeste, Arkady, Nussenzweig, André
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993211/
https://ncbi.nlm.nih.gov/pubmed/19381917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-59745-190-1_9
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