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A Gβγ Effector, ElmoE, Transduces GPCR Signaling to the Actin Network during Chemotaxis
Activation of G protein-coupled receptors (GPCRs) leads to the dissociation of heterotrimeric G-proteins into Gα and Gβγ subunits, which go on to regulate various effectors involved in a panoply of cellular responses. During chemotaxis, Gβγ subunits regulate actin assembly and migration, but the pro...
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| Publicado no: | Dev Cell |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6993146/ https://ncbi.nlm.nih.gov/pubmed/22264729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.11.007 |
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