Results of a phase 1 multicentre investigation of dexmedetomidine bolus and infusion in corrective infant cardiac surgery

BACKGROUND: Dexmedetomidine (DEX) is increasingly used intraoperatively in infants undergoing cardiac surgery. This phase 1 multicentre study sought to: (i) determine the safety of DEX for cardiac surgery with cardiopulmonary bypass; (ii) determine the pharmacokinetics (PK) of DEX; (iii) create a PK...

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Bibliografski detalji
Izdano u:Br J Anaesth
Glavni autori: Zuppa, Athena F., Nicolson, Susan C., Wilder, Nicole S., Ibla, Juan C., Gottlieb, Erin A., Burns, Kristin M., Stylianou, Mario, Trachtenberg, Felicia, Ni, Hua, Skeen, Tera H., Andropoulos, Dean B.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
Teme:
Paediatric Anaesthesia
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993105/
https://ncbi.nlm.nih.gov/pubmed/31623840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bja.2019.06.026
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