6′-Methoxy Raloxifene-analog enhances mouse bone properties with reduced estrogen receptor binding

Raloxifene (RAL) is an FDA-approved drug used to treat osteoporosis in postmenopausal women. RAL suppresses bone loss primarily through its role as a selective estrogen receptor modulator (SERM). This hormonal estrogen therapy promotes unintended side effects, such as hot flashes and increased throm...

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Publicado no:Bone Rep
Main Authors: Powell, Katherine M., Brown, Alexa P., Skaggs, Cayla G., Pulliam, Alexis N., Berman, Alycia G., Deosthale, Padmini, Plotkin, Lilian I., Allen, Matthew R., Williams, David R., Wallace, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992940/
https://ncbi.nlm.nih.gov/pubmed/32016137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bonr.2020.100246
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