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Systemic loss of Sarm1 protects Schwann cells from chemotoxicity by delaying axon degeneration

Protecting the nervous system from chronic effects of physical and chemical stress is a pressing clinical challenge. The obligate pro-degenerative protein Sarm1 is essential for Wallerian axon degeneration. Thus, blocking Sarm1 function is emerging as a promising neuroprotective strategy with therap...

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Publicat a:Commun Biol
Autors principals: Tian, Weili, Czopka, Tim, López-Schier, Hernán
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992705/
https://ncbi.nlm.nih.gov/pubmed/32001778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0776-9
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