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Evaluation of the antiviral activity of orlistat (tetrahydrolipstatin) against dengue virus, Japanese encephalitis virus, Zika virus and chikungunya virus

Many mosquito transmitted viruses of the genera Alphavirus and Flavivirus are human pathogens of significant concern, and there is currently no specific antiviral for any member of these two genera. This study sought to investigate the broad utility of orlistat (tetrahydrolipstatin) in reducing viru...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hitakarun, Atitaya, Khongwichit, Sarawut, Wikan, Nitwara, Roytrakul, Sittiruk, Yoksan, Sutee, Rajakam, Supoth, Davidson, Andrew D., Smith, Duncan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992670/
https://ncbi.nlm.nih.gov/pubmed/32001767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58468-8
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