Inhibition of Transglutaminase 2 as a Potential Host-Directed Therapy Against Mycobacterium tuberculosis

Host-directed therapies (HDTs) are emerging as a potential valid support in the treatment of drug-resistant tuberculosis (TB). Following our recent report indicating that genetic and pharmacological inhibition of transglutaminase 2 (TG2) restricts Mycobacterium tuberculosis (Mtb) replication in macr...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Palucci, Ivana, Maulucci, Giuseppe, De Maio, Flavio, Sali, Michela, Romagnoli, Alessandra, Petrone, Linda, Fimia, Gian Maria, Sanguinetti, Maurizio, Goletti, Delia, De Spirito, Marco, Piacentini, Mauro, Delogu, Giovanni
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992558/
https://ncbi.nlm.nih.gov/pubmed/32038614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03042
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