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Dose-Dependent Effects of GLD-2 and GLD-1 on Germline Differentiation and Dedifferentiation in the Absence of PUF-8

PUMILIO/FBF (PUF) proteins have a conserved function in stem cell regulation. Caenorhabditis elegans PUF-8 protein inhibits the translation of target mRNAs by interacting with PUF binding element (PBE) in the 3′ untranslated region (3′ UTR). In this work, an in silico analysis has identified gld-2 [...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Park, Youngyong, O’Rourke, Samuel, Taki, Faten A., Alfhili, Mohammad A., Lee, Myon Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992537/
https://ncbi.nlm.nih.gov/pubmed/32039211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00005
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