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Vortex fluidics-mediated DNA rescue from formalin-fixed museum specimens
DNA from formalin-preserved tissue could unlock a vast repository of genetic information stored in museums worldwide. However, formaldehyde crosslinks proteins and DNA, and prevents ready amplification and DNA sequencing. Formaldehyde acylation also fragments the DNA. Treatment with proteinase K pro...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6992170/ https://ncbi.nlm.nih.gov/pubmed/31999723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225807 |
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