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Microporous scaffolds loaded with immunomodulatory lentivirus to study the contribution of immune cell populations to tumor cell recruitment in vivo

Metastases are preceded by stochastic formation of a hospitable microenvironment known as the premetastatic niche, which has been difficult to study. Herein, we employ implantable polycaprolactone scaffolds as an engineered premetastatic niche to independently investigate the role of interleukin-10...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Bushnell, Grace G., Rao, Shreyas S., Hartfield, Rachel M., Zhang, Yining, Oakes, Robert S., Jeruss, Jacqueline S., Shea, Lonnie D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991704/
https://ncbi.nlm.nih.gov/pubmed/31544959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27179
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