Optimized monoclonal antibody treatment against ELTD1 for GBM in a G55 xenograft mouse model

Glioblastoma is an aggressive brain tumour found in adults, and the therapeutic approaches available have not significantly increased patient survival. Recently, we discovered that ELTD1, an angiogenic biomarker, is highly expressed in human gliomas. Polyclonal anti‐ELTD1 treatments were effective i...

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Publicat a:J Cell Mol Med
Autors principals: Zalles, Michelle, Smith, Nataliya, Ziegler, Jadith, Saunders, Debra, Remerowski, Shannon, Thomas, Lincy, Gulej, Rafal, Mamedova, Nadya, Lerner, Megan, Fung, Kar‐Ming, Chung, Junho, Hwang, Kyusang, Jin, Junyeong, Wiley, Graham, Brown, Chase, Battiste, James, Wren, Jonathan D., Towner, Rheal A.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991683/
https://ncbi.nlm.nih.gov/pubmed/31863639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14867
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