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Optimized monoclonal antibody treatment against ELTD1 for GBM in a G55 xenograft mouse model

Glioblastoma is an aggressive brain tumour found in adults, and the therapeutic approaches available have not significantly increased patient survival. Recently, we discovered that ELTD1, an angiogenic biomarker, is highly expressed in human gliomas. Polyclonal anti‐ELTD1 treatments were effective i...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zalles, Michelle, Smith, Nataliya, Ziegler, Jadith, Saunders, Debra, Remerowski, Shannon, Thomas, Lincy, Gulej, Rafal, Mamedova, Nadya, Lerner, Megan, Fung, Kar‐Ming, Chung, Junho, Hwang, Kyusang, Jin, Junyeong, Wiley, Graham, Brown, Chase, Battiste, James, Wren, Jonathan D., Towner, Rheal A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991683/
https://ncbi.nlm.nih.gov/pubmed/31863639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14867
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