Endothelial S1pr1 regulates pressure overload‐induced cardiac remodelling through AKT‐eNOS pathway

Cardiac vascular microenvironment is crucial for cardiac remodelling during the process of heart failure. Sphingosine 1‐phosphate (S1P) tightly regulates vascular homeostasis via its receptor, S1pr1. We therefore hypothesize that endothelial S1pr1 might be involved in pathological cardiac remodellin...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Liu, Xiuxiang, Wu, Jinjin, Zhu, Chenying, Liu, Jie, Chen, Xiaoli, Zhuang, Tao, Kuang, Yashu, Wang, Yanfang, Hu, Hao, Yu, Ping, Fan, Huimin, Zhang, Yuzhen, Liu, Zhongmin, Zhang, Lin
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991681/
https://ncbi.nlm.nih.gov/pubmed/31854513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14900
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