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Enhanced alleviation of aGVHD by TGF‐β1‐modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells

Allogeneic haematopoietic stem cell transplantation (allo‐HSCT) is the only curative method in treating haematologic malignant diseases. Graft‐versus‐host disease (GVHD) is a common complication post–allo‐HSCT, which can be life‐threatening. Mesenchymal stem cells (MSCs) as an adult stem cell with i...

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Detalles Bibliográficos
Publicado en:J Cell Mol Med
Main Authors: Wu, Ran, Liu, Chuanxu, Deng, Xiaohui, Chen, Linjun, Hao, Siguo, Ma, Liyuan
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991663/
https://ncbi.nlm.nih.gov/pubmed/31782262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14862
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