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Enhanced alleviation of aGVHD by TGF‐β1‐modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells

Allogeneic haematopoietic stem cell transplantation (allo‐HSCT) is the only curative method in treating haematologic malignant diseases. Graft‐versus‐host disease (GVHD) is a common complication post–allo‐HSCT, which can be life‐threatening. Mesenchymal stem cells (MSCs) as an adult stem cell with i...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Wu, Ran, Liu, Chuanxu, Deng, Xiaohui, Chen, Linjun, Hao, Siguo, Ma, Liyuan
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991663/
https://ncbi.nlm.nih.gov/pubmed/31782262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14862
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