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Enhanced alleviation of aGVHD by TGF‐β1‐modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells

Allogeneic haematopoietic stem cell transplantation (allo‐HSCT) is the only curative method in treating haematologic malignant diseases. Graft‐versus‐host disease (GVHD) is a common complication post–allo‐HSCT, which can be life‐threatening. Mesenchymal stem cells (MSCs) as an adult stem cell with i...

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Dettagli Bibliografici
Pubblicato in:J Cell Mol Med
Autori principali: Wu, Ran, Liu, Chuanxu, Deng, Xiaohui, Chen, Linjun, Hao, Siguo, Ma, Liyuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991663/
https://ncbi.nlm.nih.gov/pubmed/31782262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14862
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