Enhanced alleviation of aGVHD by TGF‐β1‐modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells

Allogeneic haematopoietic stem cell transplantation (allo‐HSCT) is the only curative method in treating haematologic malignant diseases. Graft‐versus‐host disease (GVHD) is a common complication post–allo‐HSCT, which can be life‐threatening. Mesenchymal stem cells (MSCs) as an adult stem cell with i...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Mol Med
Main Authors: Wu, Ran, Liu, Chuanxu, Deng, Xiaohui, Chen, Linjun, Hao, Siguo, Ma, Liyuan
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991663/
https://ncbi.nlm.nih.gov/pubmed/31782262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14862
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