Deubiquitinase inhibitor degrasyn suppresses metastasis by targeting USP5‐WT1‐E‐cadherin signalling pathway in pancreatic ductal adenocarcinoma

Wilm's tumour‐1 (WT1) is overexpressed in pancreatic ductal adenocarcinoma (PDAC) and enhances metastasis. Deubiquitination stabilizes target proteins, and inhibiting deubiquitination facilitates the degradation of target proteins. However, whether inhibiting deubiquitination of WT1 facilitates...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Cell Mol Med
Asıl Yazarlar: Li, Jiajia, Li, Haiying, Zhu, Weijian, Zhou, Bin, Ying, Jianchao, Wu, Jiansheng, Zhang, Huxiang, Sun, Hongwei, Gao, Shenmeng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991651/
https://ncbi.nlm.nih.gov/pubmed/31845546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14813
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller